Title: Association of Diabetic Retinopathy in relation with HbA1c Levels

Authors; Dr Srinivas Phani Nakkella, Dr Jayashree S Shah, Dr Sharath Kumar D Shah, Dr Sunil Kumar Kadubandi, Dr Shelly Sharma

 DOI: https://dx.doi.org/10.18535/jmscr/v7i12.121

Abstract

Purpose: To assess the association and correlation of Diabetic Retinopathy with HbA1clevels.

Materials and Methods: 100 patients of type 2 diabetics were examined in the present study.

Results: Out of 100 patients in the study, the mean age of Diabetes Mellitus is 15.99 years + 5.68 years. The mean of HbA1c in the study population was 9.25 + 1.59. The range of HbA1c was 8.6% to 10.5%.

Conclusion: The severity of Diabetic Retinopathy is increased with age and duration of Diabetes Mellitus. The HbA1c levels showed an increase, with the severity of Diabetic Retinopathy. The high HbA1c levels showed the presence of CSME (Clinically Significant Macular Edema).

Keywords: Diabetic retinopathy, NPDR, PDR, HbA1c.

References

  1. Pradeepa R, Deepa R, Mohan V Epidemiology of diabetes in India-current perspective and future projections. J Indian Med Assoc. 2002 Mar; 100(3):144-8.
  2. G, Angelou.M, Rebelakou E.F, Diabetic retinopathy: A historical assessment, Hormones 2006, 5(1):71 -74.
  3. Report on the conference on 'VISION 2020 Planning for Eastern Mediterranean Region 1 Dec. 2003, Cairo, Egypt. (WHO/EMR/PBL/03.1).
  4. Fauci AS,Braunwald E,KasperDL, Mauser DL,Longo DL, Jameson JL, et al.,editors,Harrison's Principles of internal medicine, diabetic retinopathy, 19th ed. New York:McGraw Hill;2422-2424.
  5. Diabetic Retinopathy Eye Screenings https://www.assuredwomenswellness.com/diabetic-retinopathy-eye-screenings.
  6. Sacks DB, Bruns DE, Goldstein DE, Maclaren NK, McDonald JM, Parrott M. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem. 2002;48:436-472.
  7. All Jawa, Juanita KG, Vvian A, Fonesca (2004) Diabetic Nephropathy and Retinopathy Sunil Gupta, Ajay Ambade. Prevalence of diabetic retinopathy and influencing factors amongst type 2 diabetics from central India. International J. of diabetes in developing countries.2004:24:75-78
  8. Wild S, Roglic G, Green A. Global prevalence of diabetes, estimates for the year 2000, and projections for 2030. Diabetes Care 2004;27:1047-53.
  9. Rema M, Ponnaiya M, Mohan V. Prevalence of retinopathy in non-insulin dependent diabetes mellitus at a diabetes centre in southern India. Diabetes Res ClinPract 1996; 34: 29-36.
  10. Dandona L, Dandona R, Naduvilath TJ, McCarty CA, Rao GN. Population-based assessment of diabetic retinopathy in an urban population in southern India.Br J Ophthal 1999; 83: 937-40.
  11. The Diabetes Control and Complication Trial Research Group. The effectof intensivetreatment of diabetes on the development and progression of long term complications in insulin-dependent diabetes mellitus. N.Engl J Med 1993:329:977-86.
  12. Do DV, Shah SM, Sung JU, Haller JA, Nguyen QD. Persistent diabetic macular edema is associated with elevated hemoglobin Alc.Am J Ophthalmol. 2005 Apr:139(4):620-3.
  13. Stratton I.M et.al. Association of glycemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study. BMJ 2000, 321:405-412.

Corresponding Author

Dr Srinivas Phani Nakkella

Junior Resident, Department Of Ophthalmology, SSMC, Tumkur