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Category: Volume 07 Issue 12 December 2019
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Title: Peripapillary Retinal Nerve Fiber Layer Thickness in Patients with Chronic Migraine

Authors: Dr Debabrata Das, MS (Ophthal)1, Dr Somedeb Gupta,MS (Ophthal)

 DOI: https://dx.doi.org/10.18535/jmscr/v7i12.110

Abstract

Purpose: To evaluate thickness of the peripapillary retinal nerve fiber layer (RNFL) by optical coherence tomography (OCT) among subjects with migraine headache and to compare it with healthy subjects.

Materials and Methods: This is a prospective cross-sectional study of 65 subjects with chronic migraine headache, aged between 18 and 40 years and 65 healthy subjects of same age group without headache as control group., Intraocular pressure (IOP) and axial length (AL)  were measured in each case of both the study groups.  Peripapillary RNFL was measured using OCT in all participants and then it was compared between migraine and control group.

Results: In this study, mean age of the participants was 31.84±6.03 years in migraine headache group and 31.69±5.94 years in control group. The mean duration of migraine in patients after diagnosis was 7.84±6.03 years. The average peripapillary RNFL thickness was 95.84±6.03 µm in migraine headache group and 97.32±7.08 µm in control group. The mean superior quadrant RNFL thickness was 115.84±13.03 µm in migraine headache group, 121.85±14.72 µm in control group. The average peripapillary RNFL thickness and the superior quadrant thickness was statistically significant different between migraine and control groups (p =0.0031,p =0.0150 respectively).The measurements of the RNFL thickness in inferior, temporal and nasal quadrant were not statistically significant between migraine and control groups.

Conclusion: The average and superior quadrant peripapillary RNFL were thinner in patients with chronic migraine than the healthy participants.

Keywords:  Migraine, Optical Coherence Tomography, Peripapillary RNFL.

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Corresponding Author

Dr Somedeb Gupta,MS (Ophthal)

Assistant Professor, Deptt. of Ophthalmology, Midnapore  Medical College, Paschim Medinipur,

Pin-722201, West Bengal, India