Title: Histopathological study of hysterectomy specimens in a tertiary care centre: study of 520 cases
Authors: Sarita Nair, Naisargi Patel
DOI: https://dx.doi.org/10.18535/jmscr/v7i12.94
Abstract
Background: The female genital tract is a hormone responsive system to a degree unmatched by any other system in the body. Women worldwide suffer from gynaecologic and obstetric disorders that require hysterectomy as a treatment option. The aim of the study was to evaluate all hysterectomy specimens and to study the pattern of pathological changes of different lesions occurring in cervix and uterus in relation to different age groups.
Materials and Methods: This retrospective study was conducted on hysterectomy specimens reported to Department of Pathology. Total 520 hysterectomy specimens were included in the study with age of patients varying from 20 years to 90 years. Detail clinical and other relevant history were taken followed by thorough gross examination and histopathological evaluation.
Results: Total number of hysterectomy specimen received were 520(43%). The peak age prevalence of hysterectomy was noted in the 5th decade in 173 (33%) cases. The commonest lesion encountered was leiomyoma in 192 cases (37%), 20 cases (4%) of carcinoma cervix%. and 8 cases (1.6%) of cervical dysplasia, 6cases (1.2%) of carcinoma endometrium, were encountered.
Conclusion: Study of hysterectomy specimen is fascinating as a variety of lesions are encountered. This specimen being frequently received in our department needs to be thoroughly studied in order to know the different types of histopathological lesions in female genital tract, hence histopathological examination of all hysterectomy specimens should be done and analysed.
Keywords: Hysterectomy, leiomyoma, carcinoma cervix.
References
- Samaila Modupeola et al. Clinico-pathological assessment of hysterectomies in Zaria. Eur J Gen Med. 2009;6(3):150-3.
- Perveen S, Tayyaba S. Clinicopathological review of elective abdominal hysterectomy. J of Surgery Pakistan (International). 2008;13(1):26-9.
- Sobande A, Eskander M, Archibong E, Damole I. Elective hysterectomy: A clinicopathogical review from Abha catchment area of Saudi Arabia. West African Journal of Medicine. 2005;24(1):31-5.
- Ajmera SK, Mettler L, Jonat W. Operative spectrum of hysterectomy in a German university hospital. J ObstetGynecol India 2006; 56(1): 59-63
- Yasmin, Tahira ,Javed, Saima Chaudhary, Mansab Amin. Audit of Gynaecological Hysterectomies.2010;30 (35): 30.
- MisraV, Gupta SC, Goel A, Singh PA: Reclassification of carcinoma cervix uteri by mucin histochemistry .Indian J Pathol MIcrobiol 40:463-468.1997.
- Jyothi et al. Retrospective and Prospective study of Cervical Lesions” (Dissertation); Dr. N.T.R. University of health sciences Vijaywada, Andhrapradesh 2009.
- Mahmoud K, Mahsa S, Azam M T. Histopathological Study of Hysterectomy Operations in a University Clinic in Tehran from 2005 to 2009. Journal of Family and Reproductive Health. 2011; 5:2..
- John J. Molitor. Adenomyosis: A Clinical and pathologic appraisal. Am J Obstet Gynecol 1971; 110(2): 275-84.
- Gupta G, Kotasthane DS, Kotasthane VD. Hysterectomy: A Clinico-Pathological Correlation of 500 Cases. The Internet Journal of Gynecology and Obstetrics 2010; 14 (1). DOI: 10.5580/141b.
- Diesen DL, Price TM and Skinner MA. Uterine Leiomyoma in a 14-Year-Old Girl. Eur J Pediatr Surg .2008; 18: 53-55.