Details
Category: Volume 07 Issue 12 December 2019
Hits: 978

Title: Changing Clinical and Biochemical Profile of Dengue Fever in Chittorgarh Region [Rajasthan]

Authors: Dr Anish Jain (M.D. Medicine), Dr Madhu Jain (M.D. Patho), Dr Atul Khabya (MBBS), Somil Jain

 DOI: https://dx.doi.org/10.18535/jmscr/v7i12.81

Abstract

Dengue is arboviral infection presenting with fever, arthalgia, headache, and rashes has spread to all tropical and subtropical countries. It is caused by arbovirus and transmitted by Aedes Ageypti and Aedes albopictus  mosquitoes. There are four serotypes of dengue viruses [DEN1, DEN2, DEN3, DEN4] and DEN5 is also discovered. It causes wide spectrum of illness from mild asymptomatic illness to severe fatal dengue hemorrhagic fever. The WHO in 2009, also included neurological involvement in dengue infection.

Objectives:  To Review the changing trends in Dengue last two years in chittorgarh region.

Aim: To detect the presentation and complications of Dengue fever and impact of awareness in public about the disease.

Material and Methods: This study included 200 patients of age ranging 18-70yrs admitted in medical wards with fever at GOVT. Hospital, Chittorgarh, Rajasthan, India who had positive N S 1/IgM positive. All were clinically examined, hematologic ally and biochemically tested and analyzed.

Results: We found that there is marked decrease in hemorrhagic dengue fever[DHF] and it complication in this area .

Keywords: D F, D H F, DSS Thrombocytopenia, leucopenia.

References

  1. Kasper DL, fauci AS, Hauser SL. et al. Arthropod-borne and rodent-borne virus infections. In: Harrison’s principles of internal Medicine, 19th edition [Vol2] .New York; McGraw–Hill Education 2015;P.1306
  2. National Vector Borne Disease control Programme. Dengue /dengue haemorraghic fever.2015;
  3. World Health Organization ROFSA. Comprehensive guidelines for prevention and control of dengue and dengue haemorraghic fever .2011;
  4. Dengue: Mohan DK, Shiddappa M, Dhanajaya .A study of clinical profile of dengue fever in a tertiary care teaching hospital .Sch J App Med Sci.2013:1[280-2].
  5. Rachel D, Rajamohana, Philip AZ .A study of clinical profile of dengue fever in kollam. Kerla India, Dengue Bull. 2005;29:197-202..
  6. Nimmagadda SS, Mahabala C, Boloor A, Raghuram PM, Nayak  
  7. Atypical Manifestations of Dengue Fever [DF]- Where Do We Stand Today? J Clin Diagn Res.2014;8[1] :71-3[DOI] [PubMed]
  8. Itha S,Kashyap R, Krishnani N, Saraswat  VA, Choudhuri  G, Aggarawal R. Profile of liver involvement   in dengue virus infection .Natl Med J  India 2015;18:127.
  9. Fernando S , W ijewickrama A, Gomes N,et al. Patterns and Causes of Liver Involvement In  Acute Dengue Infection.B MC Inf Dis 2016 ;16:319
  10. Seema A, Singh V, Kumar S,Kumar A, Dutta S. The changing clinical spectrum of dengue fever in 2009 epidemic in north india : A  tertiary  teaching hospital based study. J Clin Diagn Res.  2012 ;6 [6]: 999-1002
  11. Schexneider ki, Reedy EA. Thrombocytopenia in Dengue. Current Hematology Reports2005;4:145-8.
  12. Lumpaopong A, Kaewplang P, Watanaveeradej et al. Electrolyte Disturbances and abnormal urine analysis in children with dengue infection. Southeast Asian J trop Med public health 2010; 41:72-6
  13. Francisa R F. Gurreiro A, Romellia PG, et al. dengue profile of Haematological and biochemical dynamics. Rev Bras Hematol Hemoter 2012; 34:36-41
  14. Souza LJ,ALVE Sjg, Nogueria R M ,et al. Aminotransferase changes and acute hepatitis in patients with dengue fever: analysis of 1585 cases. Braz J Infect Dis 2004;8:156-63.

Corresponding Author

Dr Anish Jain (M.D. Medicine)

HOD. Medicine Dist. Hospital Chittorgarh