Title: A Comparative Study on Efficacy of Analgesic (Diclofenac) Injection versus Suppository in the Post-Operative Patient- A Systematic Review
Authors: Dr N. Junior Sundresh, U. Kiruthika, S. Somasundaram, Dr S. Narendran, K. Pravaeena, R. Rini Sally Simon
DOI: https://dx.doi.org/10.18535/jmscr/v7i12.77
Abstract
The ultimate goal of the postoperative management is to be elimination or reduction of pain and discomfort with less side effects as costeffective as possible. This study is to review the analgesic efficacy of diclofenac intramuscular injection Vs diclofenac suppositories in the post operative management. The articles published form 2000 to 2018 in MEDLINE; EMBASE from 2004- 2018 was searched. The studies were selected irrespective of type of surgery meanwhile study on postoperative management only considered. The main outcomes assessed were the Visual analogue score and adverse effect of the two different formulation of the diclofenac. Totally, 15 randomised control trial (n=1132) were considered eligible for the study as per the inclusion criteria. The VAS (Visual Analog Score) For 1, 2, 4 and 8 hours were analysed. The incidences of the Adverse effects were higher in Patients who were administered with the Intramuscular injection. On comparing the efficacy by assessing the pain score both suppositories and intramuscular injection show similar score with mild variation and suppositories have lesser adverse effect.
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