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Category: Volume 07 Issue 12 December 2019
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Title: Study of Evaluation of Platelet Count among the patient suffering from Dengue Fever Attending in Tertiary Care Hospital at N.M.C.H., Patna

Authors: Dr Arun Kumar, Dr Manohar Lal, Dr O. P. Dwivedy

 DOI: https://dx.doi.org/10.18535/jmscr/v7i12.21

Abstract

Objective: Dengue is one of the most prevalent mosquito’s borne arboviral infections in India. Seventy percent of the 96 million apparent infections occur in Asia, in which India is making up to one third of the total. Dengue fever has emerged, spread and established itself rapidly despite considerable efforts to control the mosquito populations, Aim of present study was to evaluate the platelet count of patients suffering from Dengue Fever.

Material and Methods: A total of 46 patients with different sex and age groups were  attending in the medical OPD and IPD  with clinical features of dengue infection and were dengue serologically positive were included in the study. After thorough clinical history, all the patients were subjected to proper clinical examination and referred to our department for platelet count (CBC). Platelet count was done by fully automated five part CBC machine supplied by Mindray. Platelet count was also manually evaluated.

Results: Out of the 46 dengue serological positive patients, 20 (43.48%) patients were belonged in the age group of 15 - 30 years, followed by less than 15 years of age group which was 9 (28.26 %), 31 cases (67.39 %) were males and 15 (32.61%) cases were females. Out of 46 patients, 28 (60.80%) patients had mild thrombocytopenia (platelet count 51,000 - 1 lakh), 7 cases (15.21%) had moderate thrombocytopenia (platelet count 20,000 -50,000), 4 cases (8.69%) had severe thrombocytopenia (platelet count less than 20,000), and the remaining 7 cases (15.21%) had platelet count more than 1 Lakhs. A statistically significant association was found between the age groups and severity of thrombocytopenia.

Conclusion: This retrospective study highlighted the drastic fall in the platelet count which life is threatening. More studies in this regard could further reveal the correlation between platelet count and dengue outbreaks, which would help in making the strategies and plans to forecast any outbreak in future well in advance.

Keywords: Dengue infection, Platelet count, Dengue hemorrhagic fever, Thrombocytopenia.

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Corresponding Author

Dr Manohar Lal

Assistant Professor, Department of Pathology, Nalanda Medical College, Patna, India