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Category: Volume 07 Issue 12 December 2019
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Title: Role of Contrast MRI in Detection of Breast Lesions and Histopathological Correlation

Authors: Dr N. Radha MD (RD), Dr Y. Trinadh, Dr Sravya

 DOI: https://dx.doi.org/10.18535/jmscr/v7i12.08

Abstract

Background: Breast cancer is the most common cancer in women all over India and accounts for 25% to 31% of all cancers in women in Indian cities. No preventive method for breast cancer has yet been defined. Special attention and control can so far only be planned among the known hereditary cancers. Therefore, to improve survival rate early detection is needed. The application of MRI for diagnosis of breast lesions is increasing rapidly. MRI imaging technique that employs time signal intensity curve, obtained by performing MRI scan after injection of contrast agent has emanated as amicable tool for screening of breast cancer, owing to its high sensitivity for detection of abnormalities.

Materials and Methods: Study was conducted at Department of Radio-diagnosis in Andhra Medical College, Visakhapatnam. Study population is 54 patients over duration of 2 years referred from OPD or IPD with clinically palpable breast lesions; non-palpable lesions with inconclusive findings on screening mammogram or screening ultrasonography; and high-risk patients who presented for screening MRI evaluation.

Results: The mean age of the patients was found to be 52.3 years. The range was found to be between 26 to 78 years. 11 patients (Approx. 21 %) with almost entirely fat type of fibro glandular tissue had malignant lesions. 32 cases i.e. 61% of patients showed mild background parenchymal enhancement, out of which 24 lesions were found to be malignant and 8 lesions were found to benign. 23 patients (48 %) had masses with irregular margin and 17 patients (35%) had masses with speculated margins, 8 cases (17%) had circumscribed margins.

Conclusion: DCE MRI of breast has been found to be an excellent diagnostic and screening tool for detecting and characterizing breast lesions. Evaluation is done based on morphology and enhancement pattern of the margin and an enhancement pattern of washout. Amongst these two, evaluation of morphology has emerged as the most useful and reliable parameter.

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Corresponding Author

Dr N. Radha MD (RD)

Department of Radio-Diagnosis, Andhra Medical College, Visakhapatnam, India