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Category: Volume 07 Issue 11 November 2019
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Title: Clinico-pathological Profile of Pancreatic Cancer at National Cancer Institute – Misurata Libya from Feb 2016 To Dec 2018

Authors: Mussa Elrgig, Naji Zubia, Ramadan Elamyal, Mohammed Elfaqieh, Abdallah Juwid, Feras Seaeb

 DOI: https://dx.doi.org/10.18535/jmscr/v7i11.149

Abstract

Introduction: The pancreas is a glandular organ of dual composition with both exocrine and endocrine components. Tumors of exocrine pancreas are rare with more than 95% being malignant.

Methods & Materials: This is a retrospective clinico-histopathological study of 61 cases registered in our institute  from Feb 2016 to Dec 2018. The details of patients were retrieved from patients’ files.  Information retrieved included socio-demographic data, clinical presentation, anatomical site, gross appearance, tumor stage, histopathological type and grade, presence of metastasis.

Results: During the study period, a total of 61 malignancies were registered. Of these, 23 (37%) were histopathologically confirmed pancreatic cancer. The diagnosis in the remaining 38 patients was based on clinical and radiological basis.Male to female ratio of 1.4:1. The age ranged from 40 to 90 years with a median age of 64 years. Forty nine  patients (80%) presented with abdominal pain,13 patients (21%) were jaundiced. Thehead was the most frequent site for pancreatic tumor in 48 (54%) cases followed by tail, body. Adenocarcinoma was the most common histopathological tumor in 43(90%) patients. Thirty(33.7%) patients were presented in locally advanced stages and 54(60.6 %) patients had metastasis.

Conclusion: The study was limited by being a retrospective, a relatively small number of patients and representing the experience of a single cancer institute, therefore, larger  prospective studies are recommended to study the clinicodemografic character of this disease in the country.

Keywords: Pancreatic Cancer, clinical, demographic, retrospective.

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Corresponding Author

Ramadan Elamyal

Department of Surgery, National Cancer Institute (NCI), Misurata Libya