Title: Levetiracetam Induced Hypoglycemia – A Case Report
Authors: Azma Naaz Mohammed, Narayana Geetha T.L, Sundar Raju Y.G
DOI: https://dx.doi.org/10.18535/jmscr/v7i11.118
Abstract
Hypoglycemia is a clinical syndrome with diverse causes in which low blood sugars lead to signs and symptoms thereby exposing an individual to harm. While it is a known entity in diabetics on glucose lowering drugs, hypoglycaemia in non diabetics can be caused by a variety of non diabetic drugs, including alcohol. Here we report such case of a 20 year old male patient, who was admitted with seizures and developed hypoglycaemia with levetiracetam, which was dose dependent and persistent, only to be subsiding after substitution with oxcarbazepine. Adverse effects of any drug which we know from studies and books only account to around 35% and still newer side effects can be resurfaced and encountered in our day to day practice of medicine. This article is an effort to report association of dose dependent hypoglycaemia with levetiracetam and also a step towards encouraging the adverse effect-reporting.
References
- Kilbridge PM, Campbell UC, Cozart HB, Mojarrad MG2006 Automated surveillance for adverse drug events at a community hospital and an academic medical center. J Am Med Inform Assoc 13:372–377
- Seltzer HS1989 Drug-induced hypoglycaemia A review of 1418 cases. Endocrinol Metab Clin North Am 18: 163–183
- Ioannidis JP, Lau J2001 Completeness of safety reporting in randomized trials: an evaluation of 7 medical areas. JAMA 285:437–443
- Kristen Helms and Kristi Kelley (2011). Drug-Induced Hypoglycemia, Hypoglycemia - Causes and Occurrences, Prof.EverlonRigobelo (Ed.), InTech.