Title: Spectrum of histopathological study of colonoscopic biopsies in a tertiary care hospital
Authors: B.Vani, Swathi Cheruku
DOI: https://dx.doi.org/10.18535/jmscr/v7i11.91
Abstract
Introduction: Colorectal cancer ranks second among the most common tumours of the world according to the World Cancer Report of 2000. The incidence in India is about 7/1,00,000. The increasing role of colonoscopy and polypectomy in the diagnosis and management of colorectal adenomas during the past decade has provided the histopathologist with an abundance of valuable material for study.
Materials & Methods: This was a prospective study carried out over a period of 26 months on all the colonoscopic biopsy specimens received in the Department of Pathology. All the colonoscopic biopsies received in Dept of Pathology were considered in the study. The resected specimens of large intestine were excluded from the study. All the clinical findings and radiological diagnosis were also considered.
Results: In the present study, total of 76 cases were considered. Among them 24 cases were inflammatory, 19 benign and 33 malignant lesions. Among the 76 patients, 45 were males and 31 females with a male to female ratio of 1.5:1. Age group between 41 to 50 years were most commonly affected.
Conclusion: Colonoscopic examination with biopsy may be used for follow up of Inflammatory bowel diseases and to define epithelial dysplasia in cases of chronic colitis and thus help in the early detection of carcinoma in such cases. Hence, colonoscopic biopsy has improved the role of pathologists in the diagnosis and management of large bowel diseases while underscoring a constant correlation with clinicians, but a correct interpretation still proves to be an exciting diagnostic challenge for pathologists because of small size of the specimens.
Keywords: Inflammatory bowel diseases, Papilloma, Adenocarcinoma.
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