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Category: Volume 07 Issue 11 November 2019
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Title: Sociodemographic Characteristics of Coronary Artery Disease (CAD) Patients

Authors: Dr Md. Habibur Rahman, Prof. (Dr) Md. Faruque, Dr Khondker Shaheed Hussain, Dr Md. Sirajum Munir

 DOI: https://dx.doi.org/10.18535/jmscr/v7i11.49

Abstract

Objective: In this study our main goal is to evaluate sociodemographic characteristics of Coronary artery disease (CAD) patients.

Method: This cross-sectional observational study was done in the in the NICVD, Dhakafrom October 2010 to September 2011. A total of 100 consecutive patients were included. Study populations were sub-divided into two groups on the basis of cTn I level.  In group I cTn I level ≥20ng/ml and in group II cTn I level <20ng/ml.  50 patients were included in group I and 50 patients were included in group II.

Results: In group-1 and group-2 most of patients were male, only 10% and 12% were female. Mean random blood sugar was 11.4±5.4 mg/dl in group I and 9.1±4.1 mg/dl in group II, with statistically significant difference (p=0.02) between the two groups. The mean serum creatinine of the group I was 1.0±0.2 mg/dl and of group II was 1.0±0.3 mg/dl. six percent patients had left ventricular ejection fraction (LVEF) <40%, 41% had LVEF between (40 - 49%) and 52% had LVEF at the level of (50% or >50%). In contrast, none of the patients in group II had ejection fraction <40% and 40% had ejection fraction between (40 - 49%) and 60% had ejection fraction at the level of (50% or >50%).

Conclusion: From our study we can conclude that, poor sociodemographic and economic characteristics rationally affect CAD patients. However, the result of this study needs further confirmation in a large scale multi Centre prospective cohort study. 

Keywords: Coronary heart disease (CHD), sociodemographic characteristics, serum creatinine.

References

  1. Kim MC, Kini AS, Fuster V. Definitions of acute coronary syndromes. In: Fuster V, O’Rourke RA, Walsh RA, Poole-Wilson P. Eds. Hurst’s the Heart. 12th New York, USA: McGraw Hill; 2008.1311.
  2. Yang EH, Gersh BJ, O’ Rourke RA. ST segment elevation myocardial infarction. In: Fuster V, O’Rourke RA, Walsh RA, Poole-Wilson P. Eds. Hurst’s the Heart. 12th New York, USA :McGraw Hill; 2008. 1375.
  3. Malik A. Congenital and acquired heart disease: A survey of 7062 person. Bangladesh Med Res Bull 1976; 11: 115-19.
  4. Antman, EM., Tanasijevic, MJ., Thompson, B., Schactman, M., McCabe, CH., Cannon, CP., Fischer, GA., Fung, AY., Thompson, p., Wybenga, D. and Braunwald, E. 1996, 'Cardiac specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes', N Engl J Med, vol. 335, pp. 1342-1349.
  5. Antman, EM., Bassand, JP., Klein, W. 2000, 'Myocardial infarction redefined - A consensus document of the joint European society of cardiology/ American College of Cardiology for the redefinition of myocardial infarction. The Joint European Society of Cardiology / American College of Cardiology Committee', Am J Cardiol, 36, pp. 959-969.
  6. Antman, EM., Cohen, M., Bernink, PJ., McCabe, CH., Horacek, G., Mautner, B., Corbalan, R., Radley, D. and Braunwald, E. 2000, 'The TIMI risk score for unstable angina/non-ST elevation MI: a method for prognostication and therapeutic decision making', JAMA, vol. 284, pp. 835-42.
  7. Antman , EM. 2012, 'ST-Elevation Myocardial Infarction Pathology, Pathophysiology and Clinical Features' in Bonow. RO, Mann. DL , Zipes. DP and Libby. P (eds.), Braunwald’s Heart Disease, 9th edition, Elsevier, Saunders, Philadelphia, pp. 1087-1110.
  8. Apple, FS., Quist, HE., Doyle, PJ., Otto, AP. and Mukarami, MM. 2003, 'Plasma 99th percentile reference limits for cardiac troponin and creatine kinase MB mass for use with European Society of Cardiology/American College of Cardiology consensus recommendations', Clin Chem, vol. 49, no. 8, pp. 1331-1336.
  9. Apple, FS., Smith, SW., Pears, LA., Ler, R., Murakami, MM. Benoit, MO., Levy, C., Dumas, C. and Paul, JL. 2008, 'Use of the bioMerieux VIDAS troponin I ultra assay for the  diagnosis  of myocardial infarction and adverse events in patients presenting with symptoms suggestive of acute coronary syndrome', Clinica Chimica Acta, vol. 390, pp. 72-75.
  10. Apple, FS., Pearce, LA., Smith, SW., Kaczmarek, JM. and Murakami, MM. 2009, 'Role of monitoring changes in sensitive cardiac troponin I assay results for early diagnosis of myocardial infarction and prediction of risk of adverse events', Clin Chem, vol. 55, no, 5. pp. 930-937.
  11. Atar, S. Barbagelata, A. and Birnbaum, Y. 2006, 'Electrocardiographic diagnosis of ST-elevation myocardial infarction', Cardiol Clin, vol. 24, pp. 343-365.
  12. Badimon, JJ., Ibanez, B., Fuster, V., and Badimon, L. 2011, 'Coronary thrombosis : local and systemic factors' in   V, Walsh . RA and Harrington. RA (eds.), Hurst’s The Heart,13th edition, McGraw Hill, New York,  pp. 1224-1236.
  13. Baim, DS. 2006, 'Cardiac catheterization history and current practice standards', in Baim. DS (ed.), Grossman’s cardiac catheterization, angiography, and intervention, 7th edition, Lippincott Williams and Wilkins, Philadelphia, USA, pp. 3-12.

Corresponding Author

Dr Md. Habibur Rahman