Title: Tonsillar Metastasis from Sarcomatoidcarcinoma Lung- A Rare Presentation

Authors: Lekha Madhavan Nair MD, DNB, Sindhu Nair P MD, Neelima Radhakrishnan MD, Sajeed A MD

 DOI: https://dx.doi.org/10.18535/jmscr/v7i11.02

Abstract

Carcinoma lung rarely metastasize to palatine tonsils. Tonsillar metastasis from small cell lung cancer and adenocarcinoma have been reported in literature. Here we present a rare case of tonsillar metastasis from sarcomatoid carcinoma lung with a review of the literature.

Keywords: tonsil , lung, sarcomatoid carcinoma

References

  1. Hyams VJ. Differential diagnosis of neoplasia of the palatine tonsil. Clin Otolaryngol Allied Sci 1978; 3: 117-126.
  2. Unsal M, Kutlar G, Sullu Y and Yurtlu S: Tonsillar metastasis of small cell lung carcinoma. ClinRespir J 2016 ;10: 681-683.
  3. Arroyo HH, Takehara J, Ogawa AI, Frizzarini R, Imamura R, Paula HM. Small cell lung carcinoma metastasis to palatine tonsils. Braz J Otorhinolaryngol. 2013;79: 645.
  4. Yaren A, Degirmencioglu S, Topsakal S, Yuksel S, Bir F, et al. Tonsillar metastasis from small cell lung cancer: rare but occurs. Turkish J Cancer 2009;39: 28-30.
  5. Mastronikolis NS, Tsiropoulos GE, Chorianopoulos D, Liava AC, Stathas T, et al. Palatine tonsillar metastasis from lung adenocarcinoma. Eur Rev Med Pharmacol Sci2007;11: 279-282.
  6. Wu Y, Zhu Z, Chen Y, et al. Tonsillar metastasis of non small cell lung cancer with G719S mutation in exon 18: a case report. Medicine (Baltimore) 2017; 96: e9003.
  7. Tajima S and Koda K: Palatine tonsillar metastasis of a small pulmonary adenocarcinoma showing an invasive micropapillary carcinoma pattern and Pagetoid spread at the tonsil: A case suggesting retrograde lymphatic metastasis from bulky lymph node metastases of the neck. Int J Clin Exp Pathol 8: 13601-13653, 2015.
  8. Tian Y, Han Y, Du J, Zhang Y, Liu N, Du X, et al. Palatine tonsillar metastasis of lung adenocarcinoma: an unusual immunohistochemical phenotype and a potential diagnostic pitfall. Int J Clin Exp Pathol. 2019;12(6):2288-92.
  9. Zaubitzer L, Rotter N, Aderhold C, Gaiser T, Jungbauer F, Kramer B, et al. Metastasis of pulmonary adenocarcinoma to the palatine tonsil. Molecular and clinical oncology. 2019 Feb 1;10(2):231-4.
  10. Brownson RJ, Jaques WE, Lamonte SE, Zollinger WK. Hypernephroma metastatic to the palatine tonsils. Ann Otol Rhinol Laryngol.1979; 88: 235–40.

Corresponding Author

Lekha M Nair

Senior Resident, Department of Radiation Oncology, Regional Cancer Centre, Trivandrum