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Category: Volume 07 Issue 08 August 2019
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Title: Clinical profile of 315 Dengue patients in a tertiary care centre in Kerala (India)

Authors: Jacob K. Jacob, Manjula V, Shiji K Jacob, Bhagyanath T.S.

 DOI: https://dx.doi.org/10.18535/jmscr/v7i8.168

Abstract

     

Introduction: Dengue is a major arboviral infection which poses great public health problems globally. According to WHO, around 3.9 billion people, in 128 countries, are at risk of infection with dengue virus. As there is no specific treatment for Dengue, iv fluids and paracetamol are the mainstay of treatment. This study was designed to assess the clinical and biochemical parameters of dengue fever patients admitted in medical wards of Government medical college, Ernakulam for the year 2016.

Materials and Methods: This is a Cross sectional study conducted at Department of General medicine, Government Medical College, Ernakulam, Kerala from January 2016 to December 2016. All patients admitted in medicine wards with laboratory confirmed dengue fever above the age of 12 years were included in the study. Details of history, examinations and laboratory and technical investigations reports were noted from time to time. Data were coded and entered into MS Excel. Analysis was done using S software. Quantitative variables were summarized using mean and SD.

Results and Discussion: A total of 315 patients who were admitted between January and December 2016 were studied and analysed. Majority of the patients were males (58%).Fever was seen in almost all patients. Platelet count less than 1 lakh was seen in 75 % of the patients. There was no mortality among the patients studied in our study.

Conclusions: Conservative management is required in the majority of the cases and the mortality rate is very low with adequate management. Dengue fever peaks during the monsoon period. So preventive measures carried out before that can drastically reduce the transmission of dengue.

Keywords: Dengue fever, thrombocytopenia, Kerala.

References

  1. Chakravarti A, Arora R, Luxemburger C. Fifty years of dengue in India. Trans R Soc Trop Med Hyg [Internet]. 2012; 106(5):273–82. Available from: http://dx.doi.org/10.1016/j.trstmh.2011.12.007
  2. Comprehensive guidelines for prevention and control of dengue and dengue haemorrhagic fever [Internet]. World Health Organization, Regional Publication SEARO. 2011 [cited 2018 Oct 17]. 159-168 p. Available from: http://apps.searo.who.int/pds_docs/B4751.pdf
  3. Cogan JE. Dengue and severe dengue Key facts Global burden of dengue. 2018;(February):1–7. Available from: http://www.who.int/en/news-room/fact-sheets/detail/dengue-and-severe-dengue
  4. Gubler DJ. Dengue and Dengue Hemorrhagic Fever [Internet]. Vol. 11, CLINICAL MICROBIOLOGY REVIEWS. 1998 [cited 2018 Oct 13]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC88892/pdf/cm000480.pdf
  5. Banerjee I. Dengue: The break-bone fever outbreak in Kerala, India. Nepal J Epidemiol [Internet]. 2017 Jun [cited 2018 Sep 19];7(2):666–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29181227
  6. Daniel R, Zachariah Philip A. A Study of Clinical Profile of Dengue Fever in Kollam, Kerala, India ¶ [Internet]. Vol. 29, Dengue Bulletin. 2005 [cited 2018 Nov 26]. Available from: http://apps.who.int/iris/bitstream/handle/10665/164052/dbv29p197.pdf?sequence=1&isAllowed=y
  7. Karunakaran A, Ilyas WM, Sheen SF, Jose NK, Nujum ZT. Risk factors of mortality among dengue patients admitted to a tertiary care setting in Kerala, India. J Infect Public Health [Internet]. 2014 Mar 1 [cited 2018 Sep 19];7(2):114–20. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24290074
  8. ShijiPV, Thulaseedharan NK, Chandni R. DENGUE FEVER EPIDEMIC-A CLINICAL STUDY IN A TERTIARY CARE CENTRE International Journal Of Recent Scientific Research. Off Publ Int J Recent Sci Res Off Publ Int J Recent Sci Res [Internet]. 2016 [cited 2016 Oct 28];7(6). Available from: http://www.recentscientific.
  9. Tewari K, Tewari VV, Mehta R. Clinical and hematological profile of patients with dengue fever at a tertiary care hospital - An observational study. Mediterr J Hematol Infect Dis [Internet]. 2018 Jan 18 [cited 2018 Nov 25];10(1):202. Available from: http://www.ijmedicine.com/index.php/ijam/article/view/920
  10. Deshwal R, Qureshi MI, Singh R. Clinical and laboratory profile of dengue fever. J Assoc Physicians India. 2015;63(DECEMBER2015):30–2.
  11. Turbadkar D, Ramchandran A, Mathur M, Gaikwad S. Laboratory and clinical profile of dengue: A study from Mumbai. Ann Trop Med Public Heal [Internet]. 2012;5(1):20. Available from: http://www.atmph.org/text.asp?2012/5/1/20/92873
  12. Sharma S, Sharma ″ SK, Mohan A, Wadhwa J, Dar L, Thulkar S, et al. Clinical Profile of Dengue Haemorrhagic Fever in Adults during 1996-Outbreak in Delhi [Internet]. Vol. 22, Dengue Bulletin. 1998 [cited 2018 Oct 14]. Available from: http://apps.who.int/iris/bitstream/handle/10665/148654/dbv22p20.pdf?sequence=1
  13. Bhalla A, Singhal M, Suri V, Singh V, Varma S. Clinical profile of dengue fever in a tertiary care centre in North Western India. Int J Infect Dis [Internet]. 2014 [cited 2018 Nov 26];21:1–460. Available from: http://dx.doi.org/10.1016/j.ijid.2014.03.1089

Corresponding Author

Jacob K Jacob

Professor, Department of Internal Medicine, Government medical college, Ernakulam, Kalamassery,

HMT P.O, India, Kerala. Pin- 683503