Title: Analysis of the Common Causes of Blood Donor Deferral in a Tertiary Care Hospital Indore: A Single-Center Study

Authors: Dr Zoya Khan, Dr C.S. Chhatrasal, Prof. Dr Ashok Yadav, Dr Pankaj Shinde

 DOI: https://dx.doi.org/10.18535/jmscr/v7i8.148

Abstract

        

Background: We aimed to conduct a retrospective study in order to statistically analyze the common causes for blood donor rejection in a tertiary care center at Indore according to the American Association of Blood Banks. The analysis of the pattern of deferral and interventions to bring back deferred donors when possible could be a strategy for long-term retention of motivated blood donors.

Subjects and Methods: A sample of 2492 rejected donors was randomly selected from a single blood bank between June 2016 to July 2019. The evaluation of blood donors was medical according to the personal history questionnaire and a medical examination done before the blood donation proceeded.

Results: The causes of deferral were categorized into three main categories: personal factors, examination and medical history. The most common personal cause of deferral was alcohol(7.5%); however, the most common medical examination cause of deferral was anaemia (36.3%)Concerning the medical history, the commonest cause was medication.(13.3%).

Conclusion: Anaemia (36.3%), medication (13.3%) and alcohol (7.5%); were the major causes of rejection in this study. Similarities and variations between the commonest causes of blood donor rejection may be due to the differences and similarities in the geographic area and in the cultural, educational and socioeconomic factors.

Keywords:  Donor questionnaire, blood transfusion, safe blood.

References

  1. Tariq S, Tariq S, Jawed S, Tariq S. Knowledge and attitude of blood donation among female medical students in Faisalabad. J Pak MedAssoc. 2018;68(1):65–70.
  2. Department of Essential Health Technologies Blood Transfusion Safety Unit. Universal Access to Safe Blood Transfusion. Geneva: World Health Organization; 2008.
  3. World Health Organization. Blood Donor Selection: Guidelines on Assessing Donor Suitability for Blood Donation. Geneva: World Health Organization; 2012:16–23.
  4. Gillet P, Neijens E. An original approach to evaluating the quality of blood donor selection: checking donor questionnaires and analyzing donor deferral rate. Front Med. 2018;5:74.
  5. Katz L, Strong DM, Tegtmeier G, Stramer S. Performance of an algorithm for the reentry of volunteer blood donors deferred due to false positive test results for antibody to hepatitis B core antigen. Transfusion. 2008;48(11):2315–2322.
  6. Gonçalez TT, Sabino EC, Schlumpf KS, et al. Analysis of donor deferralat three blood centers in Brazil. Transfusion. 2013;53(3):531–538.
  7. Arslan Ö. Whole blood donor deferral rate and characteristics of the Turkish population. Transfus Med. 2007;17 (5):379–383.
  8. Bahadur S, Jain S, Goel RK, Pahuja S, Jain M. Analysis of blood donor deferral characteristics in Delhi, India. Southeast Asian J Trop MedPublic Health. 2009;40(5):1087–1091.
  9. Lim JC, Tien SL, Ong YW. Main causes of pre-donation deferral of prospective blood donors in the Singapore Blood Transfusion Service. Ann Acad Med Singapore. 1993;22(3):326–331.
  10. Al Shaer L, Sharma R, Abdulrahman M. Analysis of blood donor predonation deferral in Dubai: characteristics and reasons. J Blood Med.2017;8:55–60.
  11. Bashawri LA. A review of predonation blood donor deferrals in a university hospital. J Family Community Med. 2005;12(2):79–84.
  12. Abdelaal M, Anwar F. Analysis of blood donor deferral in Jeddah, Saudi Arabia: characteristics and causes. J Pak Med Assoc. 2016;66(11): 1392–1395.
  13. org [homepage on the Internet]. Bathesda: AABB Blood FAQ.2019. Available from: http://www.aabb.org/tm/Pages/bloodfaq.aspx. Accessed August 18, 2017
  14. Hildrum B, Mykletun A, Holmen J, Dahl AA. Effect of anxiety and depression on blood pressure: 11-year longitudinal population study. Br J Psychiatry. 2008;193(2):108–113.
  15. Newman BH. Adjusting our management of female blood donors: The key to an adequate blood supply. Transfusion  2004;44:591–6. [PubMed] [Google Scholar]
  16. Qureshi NA, Ali GI, Abushanab TS, et al. History of cupping (Hijama): a narrative review of literature. J Integr Med. 2017;15(3):172–181.
  17. Fowler PM, Paul DJ, Tomazoli G, Farooq A, Akenhead R, Taylor L.Evidence of sub-optimal sleep in adolescent Middle Eastern academy soccer players which is exacerbated by sleep intermission proximal to dawn. Eur J Sport Sci. 2017;17(9):1110–1118.
  18. Halperin D, Baetens J, Newman B. The effect of short-term, temporary deferral on future blood donation. Transfusion. 1998;38(2): 181–183.
  19. Nordenberg D, Yip R, Binkin NJ. The effect of cigarette smoking on hemoglobin levels and anemia screening. JAMA. 1990;264(12):1556–1559.
  20. Madani TA. Sexually transmitted infections in Saudi Arabia. BMC Infect Dis. 2006;6(1):3.
  21. Abdalla SI, Malik EM, Ali KM. The burden of malaria in Sudan: incidence, mortality and disability-adjusted life-years. Malar J. 2007;6(1):97.

Corresponding Author

Dr C.S. Chhatrasal

Associate Professor, Department of Pathology, Mahatma Gandhi Medical College, Indore, Madhya Pradesh, India