Title: Prevalence of dyslipidemia in patients with type 2 diabetes mellitus: a cross sectional study
Authors: Dr Sandeep Singh, Dr Tarunendra Kumar Mishra
DOI: https://dx.doi.org/10.18535/jmscr/v7i8.138
Abstract
Background: One of the major risk factors for cardiovascular disease in diabetes mellitus is dyslipidemia. It is characterised by high plasma triglyceride level, low HDL cholesterol level and increased level of small dense LDL-cholesterol particles. The prevalence of hypercholesterolemia is not increased in patients with diabetes mellitus, but mortality from coronary heart disease (CHD) increases with serum cholesterol levels, and lowering of cholesterol with drug therapy reduces diabetic patient’s cardiovascular risk.
Methods: The cross sectional study was conducted on patients consisting of 100 (50 male and 50 female) known type 2 diabetes mellitus. Age, gender, duration of disease, body mass index (BMI) was recorded in all patients. Fasting blood glucose levels, total cholesterol, triglycerides, HDL, LDL, VLDL levels were measured using standard methods and recorded.
Results: The serum parameters TC, TG, HDL, LDL, and VLDL were significantly correlated to FBG levels in both diabetic and non-diabetic subjects. The variables were also significantly associated among each other in T2DM patients.
Conclusion: The present study provides evidence to suggest that lipid variables are associated with each other in T2DM patients among the population.
Keywords: Coronary heart disease, Type 2 diabetes mellitus, body mass index.
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