Title: Cytomorphological Patterns of Focal Nodular Lesions of Liver at a Tertiary Care Hospital

Authors: Dr Prachi Gupta, Dr Aakansha Shukla, Dr Ashok Singh, Dr Alpana Jain, Dr Sangita Sehgal, Dr Ruchi Agarwal

 DOI: https://dx.doi.org/10.18535/jmscr/v7i8.113

Abstract

USG guided Fine needle aspiration cytology (FNAC) is an  important  and  valuable technique for diagnosing benign and malignant space occupying lesions  of liver.In present study all cases

Coming to Sawai Man Singh Hospital Jaipur from July 2018 to December 2018 with focal nodular lesions in liver and adequate cellularity were included. Age range was 32 to 75 years. Primarily the diagnosis was made on May-Graunwald-Giemsa, Hematoxylin and Eosin (H and E).Maximum number of patients (43%) presented with clinical feature of pain in right hypochondrium. Cytomorphologically out of total 100 cases 23% were benign and 77% were neoplastic. Out of total benign lesions 34.7% were of cirrhosis and least 4.34% were of granulomatous lesions and dysplastic nodule each. .Out of total 77neoplastic lesions maximum 40.2% were metastatic, 28.55% of primary hepatocellular carcinoma and least 1.2% were of Hepatoblastoma embryonal type and small cell neuroendocrine carcinoma. Out of total 31metastatic lesions maximum 12 were from lung carcinomas and only 1 case of plasma cell myeloma. FNAC is a safe and cost effective method that can differentiate benign and malignant lesions accurately.

Keywords: Liver SOL, Hepatocellular carcinoma, Cirrhosis, Malignant epithelial neoplasm.

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Corresponding Author

Dr Ruchi Agarwal

Assistant Professor, Dept of Pathology, SMS Medical College Jaipur, Rajasthan, India