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Category: Volume 07 Issue 08 August 2019
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Title: Effects of Consangineous Marriages Maternal Teratogenecity and Antenatal Maternal Illness on Neonatal Congenital Aanomalies

Authors: Dr Nilesh Santaji Karpe, Dr Dipak Ramdas Kamat, Dr Sayed Asif Umar

 DOI: https://dx.doi.org/10.18535/jmscr/v7i8.99

Abstract

Maternal factors greatly influence the neonatal congenital anomalies Infection of the fetus by rubella, cytomegalovirus, varicella and toxoplasma can be teratogenic13. Exposure of the fetus to some medication can cause congenital anomalies. Some maternal health conditions have shown increased risks for congenital anomalies including obesity, insulin-dependent diabetes, various forms of folate deficiencies and phenylketonuria19. Pregnancy induced hypertension, vaginal bleeding early in pregnancy, twin pregnancy, oligohydramnios, polyhydramnios, breech presentation, period of gestation, antenatal care during pregnancy, history of previous abortions and still  births have been observed to be maternal factors associated with congenital anomalies.

Aims and Objective: To study the proportion of congenital anomalies at tertiary rural health careand to find the corelation in between the antenatal maternal illness maternal teratogenicity, cooking sources of the mother  consangineous marriage , liquor status of anc on usg and neonatal congenital anomalies

Sample Size: We took a sample size of 150 patients.. All neonates diagnosed with any congenital anomalies born in or coming to nicu of prh.

Results: Proportion of congenital anomalies were seen more in consanguineous marriage and in the mothers with antenatal illness .teratogenicity also had a significant rolec.

Conclusion: Regular check up of the mother and proper counseling for non addiction and avoidance of consanguineous marriage and simple diagnostic means such as x-ray and ultrasound can help in reducing the number of anomalies.

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Corresponding Author

Dr Sayed Asif Umar