Title: A Prospective Study of Changing Trend in the Clinical and Ultrasonographic Case Profile of Amoebic Liver Abscess – HIV Correlation and the Surgical Implications - In a Tertiary Care Hospital in North Andhra Pradesh

Authors: Dr Y.Padmanabham M.D (Micro), Prof. S. Srinivas M.D (GM), Dr P. K.  Ranga Rao, Dr K.Kodanda Rao M.S (G.S)

 DOI: https://dx.doi.org/10.18535/jmscr/v7i8.55

Abstract

Introduction: In India due to poor sanitary condition and a lower socioeconomic status amoebiasis is endemic and amoebic liver abscess accounts for 3-9% of all cases of amoebiasis. Amoebic liver abscess (ALA) is the commonest extra intestinal manifestation of amoebiasis.

Aim: The aim of this work is to study the various presentations of amoebic liver abscess and HIV correlation to find any change in the clinical and radiological profile of ALA in recent years and to compare with other studies.

Materials and Methods: This study is conducted prospectively over a period of 2 years from December 2015 to November 2017 in the department of General Medicine, Andhra Medical College and King George Hospital, Visakhapatnam, Andhra Pradesh.

Study Design: Observational study.

Sample Size: Eighty patients were the confirmed diagnosis of ALA are included in this study.

Study Subjects: All patients who fulfill the diagnostic criteria for amoebic liver abscess are included in the study.

Results: In the present study, the incidence of amoebic liver abscess in the year 2016 is estimated to be 0.58/1000/year of 61,732 patients admitted in King George Hospital, Visakhapatnam whereas the incidence of HIV positive with amoebic liver abscess in the year 2016 is only 0.08/1000/year. Among HIV patients ALA is more intense in presentation and treatment if challenging.

Discussion: The present study has shown that the patterns of ALA largely parallels what has been established previously in terms of age, sex, onset, risk factors, clinical manifestations, number, size and location of abscess, treatment modalities and prognosis with few modifications.

Conclusions: It is concluded that amoebic liver abscess is a treatable condition having a good prognosis if it is recognized early and treated appropriately particularly among HIV patients.

Keywords: ALA, HIV, Clinical, Radiological, study.

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Corresponding Author

Dr K.Kodanda Rao M.S (G.S)

Faculty, Dept of General Surgery, Gitam Institute of Medical Sciences and Research, Gitam Deemed to be University, Visakhapatnam, Andhra Pradesh, India