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Category: Volume 07 Issue 08 August 2019
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Title: A Study of Effect of Fluid Restriction on Mortality and Morbidity Pattern in Term Neonates with Perinatal Asphyxia Admitted In NICU, KGH

Authors: Dr Prema Sekhar, Dr Pushpa Priyanka

 DOI: https://dx.doi.org/10.18535/jmscr/v7i8.44

Abstract

Introduction: Perinatal Asphyxia is one of the commonest Neonatal problems and contributing significantly to Neonatal Morbidity and Mortality.  This study is done for controlling the consequences of Hypoxic Ischaemic Encephalopathy following Perinatal Asphyxia with careful management of fluid and avoidance of Cerebral Edema.

Aims and Objectives

  1. To assess the effects of Fluid Restriction (FR) and Full Fluid (FF) administration on mortality and morbidity patterns in term neonates with Perinatal Asphyxia.
  2. Comparison of occurrence of seizures in FR and FF group.

Materials and Methods: This is prospective study conducted in babies admitted in NICU, KGH with Perinatal Asphyxia from May2018 to May2019.  62 babies were included in this study and 31 were subjected to FR. (2/3rd of total requirement)

Inclusion Criteria: Term neonates>37weeks with Perinatal Asphyxia (In Born, Out Born with APGAR<6) at 5min admitted in KGH

Exclusion Criteria

  1. Preterm babies
  2. Babies with Congenital Malformations, Renal Failure, Suspected Metabolic Disease, MAS, Congenital Infections.

Results: 62 babies admitted in NICU are grouped into FR (31) and FF(31) of that 17% Mortality noted in FR group and 3.5% FF group. In FR group progression of HIE-II to HIE-III is more and there is less frequency of seizures in FR group

Conclusions: FR group showed increased encephalopathy and more chances of AKI In fluid restricted group and no significant change in mortality. There is decreased frequency of seizures in FR group.

References

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Corresponding Author

Dr Prema Sekhar

Post Graduate, Department of Pediatrics, Andhra Medical College