Title: End tidal carbon dioxide (EtCO2) and hemodyanamic changes following tourniquet release in lower limb surgery under general anesthesia

Authors: Diptimayee Mallik, Bhavna Sriramka, Sudeep Mohapatra, Megha Khetan

 DOI: https://dx.doi.org/10.18535/jmscr/v7i8.16

Abstract

Utilization of pneumatic tourniquet is a normal practice in most appendage medical procedures for orthopedic, plastic/reconstructive surgery to acquire a bloodless field. this study to analyze the end tidal CO2 and hemodynamic changes following tourniquet release in lower limb surgeries under General anaesthesia. A total of  150 patients of ASA physical status Class I and II, of either sex in the age group of 18 to 55 years who underwent  elective surgery on the lower limbs using pneumatic tourniquet , under General anaesthesia were considered, Data collected 4 times during General anaesthesia, 15 minutes after  induction of anaesthesia, 30 minutes after inflation  of tourniquet, 5minutes after deflation and 15 minutes after deflation of tourniquet. Heart rate during the period of tourniquet inflation it is remains same or slightly increased to a mean of 103.05 ± 15.50 beats/min. But after the tourniquet deflation the heart rate showed a progressive rise. The peak increase was seen immediately after the tourniquet release (after 5 minutes) by 123±16.04 beats/min. During 30 minutes after tourniquet the MAP remains same or may increase slightly to 95.489±2.44 mm Hg which is statistically significant. Then 5 minutes after tourniquet deflation there is sudden and gross decrease in MAP to 85.37±4.88 mmHg. the EtCO2 30 minutes after tourniquet inflation was more or less equal that is 31.316±1.38 mmHg. Then at tourniquet deflation after 5 minutes there is rise of EtCO2 to 41.317±1.913mmHg then it gradually comes to baseline.  Heart rate, ETCO2 , and mean arterial pressure showed minimal change during inflation phase while there occurs significant change after deflation.

Keywords: Tourniquet, EtCO2 , Hemodyanamic, Tourniquet inflation.

References

  1. Klenerman L. The tourniquet in surgery. The Journal of Bone and Joint 1962;44B:937–43.
  2. Denis L. Bourke, Marc S. Silberberg, Rafael Ortega, and Marcelle M. Willock, Respiratory Responses Associated with Release of Intraopera tive Tourniquets. ANESTH ANALG 1989:69:541-4
  3. Lam A.M., Hirst, R.P., Slee, T.A. changes in cerebral blood flow velocity after release of intraoperative tourniquet in humans : A transcranial doppler study. Anesth Analg 1990;71: 503-10.
  4. Takahashi S, Mizutani T, Sato S. Changes in oxygen consumption and carbon dioxide elimination after tourniquet release in patients breathing spontaneously under epidural anesthesia. Anesthesia and Analgesia1998; 86: 90–4.
  5. Estebe JP, Malledant Y. Pneumatic tourniquets in orthopedics.Ann Fr Anesth Reanim 1996 ; 15 : 162-178.
  6. Girardis M, Milesi S, Donato S, et al.The hemodynamic and metabolic effects of tourniquet application during knee surgery. Anesthesia and Analgesia2000; 91: 727–31.
  7. Kaufman RD, Walts LF. Tourniquet-induced hypertension. Br J Anaesth 1982;54:33H.
  8. Townsend HS, Goodman SB, Schurman DJ, Hackel A, Brock-Utne JG. Tourniquet release: systemic and metabolic effects. Acta Anaesthesiologica Scandinavica 1996; 40: 1234–7.
  9. Samii K, Elmelik, E. Mourtada, M B., Debeyre J, Rapin M. Intraoperative hemodynamic changes during total knee replacement, Anesthesiology 1979; 50: 239-42.
  10. Zaman SM, Islam MM, Chowdhury KK, Rickta D, Ireen ST, Choudhury MR, Alam M. Haemodynamic and end tidal CO2 changes state after inflation and deflation of pneumatic tourniquet on extremities. Mymensingh Med J. 2010 Oct;19(4):524-8.
  11. Deen L, Nyst CL, Zuurmond WW. Metabolic changes after tourniquet release. Acta Anaesthesiol Belg. 1982;33(2):107-14.
  12. Patel A.J., Choi C.S., Giuffrida J.G: Changes in end tidal CO2 and arterial blood gas levels after release of tourniquet, Southern Medical Journal 1987; 80: 213-6.
  13. Dickson M, White H, Kinney W, Kambam JR. Extremity tourniquet deflation increases end-tidal pCO2. Anesth Analg 1990; 70: 457–8.
  14. Lee TL, Tweed WA, Bachan S. Oxygen consumption and carbon dioxide elimination after release of unilateral lower limb pneumatic tourniquets. Anesth Analg 1992;75:113–7.
  15. Sharrock, N.; Go, G.; Sculco, T. Effect of thigh tourniquet deflation on hemodynamic variables assessed by measuring suprasystolic brachial artery signals: A-149 European Journal of Anaesthesiology: June 2006 - Volume 23 - Issue - p 39.

Corresponding Author

Megha Khetan

Department of Anaesthesiology and Critical Care, IMS and SUM hospital, Siksha “O” Anusandhan University (Deemed to be), K8, Kalinga nagar, Bhubaneswar-751003, Odisha, India