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Category: Volume 07 Issue 05 May 2019
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Title: A Study of Prevalence and Antimicrobial Susceptibility Pattern of Non Fermenter Gram Negative Bacilli Isolated From Various Clinical Samples at a Tertiary Care Center, Jaipur

Authors: Anshu Shastri, Bilal Ahmed Malik, Dr Mohammad Suhaib, Dr Grace John, Dr Shipra Sharma

 DOI: https://dx.doi.org/10.18535/jmscr/v7i5.110

Abstract

Background: The present study was done to examine the prevalence and antimicrobial susceptibility pattern of NFGNB. 

Introduction: Non Fermenter Gram Negative Bacilli were previously considered as Non-pathogenic or contaminants but in past few years they have become a serious threat to the society as the frequency of their isolation and resistance towards antimicrobial agents is increasing rapidly. They have developed resistance towards commonly used antimicrobial agents as well as towards higher class also.

Material & Methods: This study was done on all clinical samples received for culture and sensitivity over a period of 6 months in department of Microbiology, NIMS Medical College, Jaipur. Samples were received and processed according to standard procedures and Antimicrobial susceptibility testing was done by using Kirby Bauer’s disc diffusion method.

Result: From 674 bacterial isolates, 122 isolates (18.10%) were identified as NFGNB. Male population was highly affected by NFGNB as compared to female population. Pseudomonas species was commonly isolated followed by Acinetobacter species and Proteus species. Meropenem was most sensitive drug followed by Imipenem. Cephalosporins showed high resistance.

Conclusion: Higher isolation rate of NFGNB seen in our study with high resistance towards first line antibiotics. Resistance towards Cephalosporins and Carbapenems indicates Beta-lactamases production by these organisms. So this study will be helpful in initiating proper empirical therapy of such patients, thus reducing the morbidity rate.

Keywords: NFGNB, Pseudomonas species, Acinetobacter species, Proteus species, Kirby-Bauer’s disc diffusion method, Carbapenem, Cephalosporins.

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Corresponding Author

Dr Mohammad Suhaib

Assistant Professor, Department of Microbiology, National Institute of Medical Sciences & Research, NIMS University, Jaipur, Rajasthan, India