Title: A Study on Lung Cancer in non Smokers and Smokers in a Tertiary Care Hospital of Eastern India
Authors: Dr Anamika Verma, Prof. Dr Subhra Mitra, Prof. Dr Rajendra Prasad, Dr Mohd. Arif Siddiqui, Dr Rishabh Kacker
DOI: https://dx.doi.org/10.18535/jmscr/v7i5.88
Abstract
Background: Lung cancer contributes to the majority of all cancer diagnosis in the world. It has the most unfavourable prognosis and accounts for the maximum number of cancer related deaths worldwide. In our study we have compared epidemiology and clinic radiological profile of lung cancer among smokers and non smokers
Methods: 44 lung cancer patients were enrolled. They were subjected to diagnostic procedures like transthoracic FNAC/biopsy, bronchoscopy, closed pleural biopsy, lymph node FNAC/biopsy, besides routine blood and sputum examinations and CECT thorax. Data was analysed after 6 months.
Results: Age of most patients was between 46 and 60 years. Lung cancer among smokers was significantly high in males.59% of lung cancer patients were residents of rural areas.63.7 % of study population were illiterate and 63.7% were Hindu.93% of non smokers and 23 % smokers had cough and wheeze at presentation respectively.21.4 % of non smokers and 16.6% of smokers with lung cancer had pericardial effusion. The commonest radiological presentation of smokers with lung mass was mass lesion and mediastinal lymph nodes.57.3% of non smokers with lung cancer presented with pleural effusion. Smokers mainly presented with mass in right upper lobe and non smokers presented with mass in left lower lobe.23.3 % of smokers with lung cancer had COPD whereas 7.3% of nonsmokers were hypertensive and diabetic.63.8 % of smokers and 43% of non smokers had squamous cell carcinoma. Smokers with pack years >30 suffered from squamous cell carcinoma and those with <5 pack years suffered from adenocarcinoma.50 % and 35.8 % 0f squamous cell carcinoma presented with central mass in smokers and non smokers respectively.35.7% of smokers and 3.3 % of non smokers were addicted to non smoking form of tobacco.
Conclusion: Squamous cell carcinoma is predominantly present in smokers however 43% of non smokers also suffered from same. COPD, hypertention and diabetes was not significantly correlated with bronchogenic carcinoma.
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