Title: Comparison of Breast Density Assessment by Visual and Quantra software

Authors: Sumeena Shanmugam, Ushanandhini.G, Devimeenal.J

 DOI: https://dx.doi.org/10.18535/jmscr/v7i5.32

Abstract

Aim: To compare the breast density assessment visually and by Quantra software.

Materials and Methods: Digital mammographic exams of (771 right breast, 796 left breast, total 1567 examinations)   women participating in breast cancer clinic (age 30–83 years) were included from October 2018 to march 2019. Breast density was assesed visually as per Breast Imaging Reporting And Data System (BIRADS 5th edition) and compared with automated Quantra software (Hologic, selenia) and to establish the role of the software in clinical practice. kappa value was calculated to assess the degree of agreement among visual and Quantra assessment. Chi-square test is used to assess the significance in the distribution of different breast densities in different age groups.

Results: The distribution of density was significantly different by Visual assessment and by quantra except BIRADS category D. Quantra assessed  BIRADS A,B category  (24.9% in right side, 29.9% in left side ) less compared to visual assessment (33.8%in right side , 35.0% in left side)  and more of  C category ( 63.0%n right side,60.9%in left side  ) than visual (54.10% in right side,52.90 %  in left side).The different density patterns of breast in each age group are statistically significant in both visual assessment and quantra.

Conclusion: More number of visual fat densities (category A) were assessed as scattered fibroglandular densities (category B) by Quantra. Visual scattered fibroglandular densities (category B) were assessed as heterogenous fibroglandular densities (category C) by Quantra .These are the reasons for the disagreement among visual and Quantra assessment. Quantra assessed breast density is reproducible, and is preferred to visual assessment in risk assessment.

Keywords: Mammography, BI-RADS breast density categoryautomated volumetric breast density measurement, quantra ,screening mammography.

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Corresponding Author

Sumeena Shanmugam

Asst Professor, Department of Radiodiagnosis, Govt. Kilpauk Medical College, Chennai, Tamil Nadu, India