Title: A Rare Case of Benign Breast Tumor – Adenomyoepithelioma

Authors: A.Haretha, K. Ambedkar Raj, G.Jeevaraj, V. Sarada

 DOI: https://dx.doi.org/10.18535/jmscr/v7i2.132

Abstract

Introduction

Benign adenomyoepithelioma of the breast is a rare tumor characterized by biphasic proliferation of both an inner layer of epithelial cells and a prominent peripheral layer of myoepithelial cells. It was first described by Hamperl[1] in 1970. Benign adenomyoepitheliomas outnumber their malignant counterparts by far. Malignancy may arise either through malignant transformation of 1 of the 2 cellular components or through malignant transformation of both. The difficult differential diagnosis, potential for recurrence and malignant evolution of this lesion merit a careful approach

Clinical Presentation

A 43-year-old woman presented with a swelling in left breast for the past 8 months. On examination, a 3 × 2.5 x 2 cm firm, non-tender, and mobile mass was palpated. Fine needle aspiration cytology of the mass showed clusters and sheets of ductal epithelial cells with apocrine metaplasia and hyperplasia along with clusters of myoepithelial/ stromal cells in background of eosinophilic fluid and cyst macrophages (figure1,2). Hence a diagnosis of a Fibrocystic disease was made on cytological evaluation. Subsequently the mass was excised in toto and sent for histopathological examination.

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Corresponding Author

A Haretha

Postgraduate, Trichy SRM Medical College, Hospital & Research Center, Trichy