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Category: Volume 06 Issue 12 December 2018
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Title: Evaluation of thyroid dysfunction by estimation of serum thyroid stimulating hormone and thyroid hormones in a tertiary care hospital in Assam

Author: Julie Sarmah

 DOI: https://dx.doi.org/10.18535/jmscr/v6i12.167

Abstract

Thyroid hormones are necessary for maintenance of balance in various metabolic functions of the body. Thyroid dysfunction leads to manifestation of hypothyroidism or hyperthyroidism which may be subclinical or overt. The prevalence of this dysfunction varies worldwide depending on many factors. The data available for the dysfunction in Indian population especially of Assam is very scanty. Therefore, the present study was undertaken to evaluate the prevalence of thyroid dysfunction amongst the patient attending different clinics in Tezpur Medical College and Hospital which caters to population of Assam residing on the north bank of river Brahmaputra. All the reports of serum TSH , TT4 and TT3 obtained from the samples collected from the OPD and indoor patients as per the requisition made by the clinicians  and samples analysed in VitrosECi immunodiagnostic system, except that of  neonates, ICU patients and haemolysed samples were statistically analysed. Out of total 11189 samples of the study population 9314(83.24%) were euthyroid and 1875 (16.76%) had thyroid dysfunction. Subclinical hypothyroidism 1342(11.99%) was commonest dysfunction with female preponderance 1000(53.33%) followed by subclinical hyperthyroidism 344( 3.07%).In the age group between 21-40 years the dysfunction was more prevalent. An extensive study may be carried out considering the estimation of antithyroid antibodies, urinary iodine, dietary factors and effect of drugs on thyroid hormones to find out the etiological factors for the better diagnosis and treatment of the dysfunction.

Keywords: Anterior pituitary gland, Atherosclerosis, Euthyroid, Hyperthyroidism, Hypothyroidism, Myxoedema Coma, Osteoporosis, Total Triiodothyronine (TT3), Total Thyroxine (TT4), Thyroid stimulating hormone (TSH).

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Corresponding Author

Julie Sarmah

Associate Professor of Biochemistry, Tezpur Medical College, Bihaguri, Tezpur-784010, Assam, India

Phone: +91 88110 98895, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.