Title: Ileal mucormycosis in an immunocompetent individual presenting as septic shock: One of its kind presentations
Authors: Mathi Manoj Kumar R, Jagadeesh C, Madhumitha R, Ram Gopalkrishnan
DOI: https://dx.doi.org/10.18535/jmscr/v6i8.92
Abstract
Mucormycosis is a fatal invasive fungal infection caused by members of class Phycomycetes, mainly mucoraceae. It is associated with immunocompromised patients, uncontrolled diabetics, malignancies, post transplant recipients, long term steroid users, and in acidosis or deferoxamine administration where there is increased availability of iron. Recently, there is a sharp rise in incidence amongst immunocompetent individuals. Gastrointestinal mucormycosis (GIM) is an unusual form of presentation of this lethal fungal infection. Here we present a case of a young middle aged immunocompetent individual, presenting with septic shock and later diagnosed as GIM.
Keywords: Gastrointestinal Mucormycosis, septic shock, immonocompetent individuals.
References
- Kwon-Chung K. Taxonomy of fungi causing mucormycosis and ento- mophthoramycosis (zygomycosis) and nomenclature of the disease: molecular and mycologic perspectives. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2012; 54(S1): S8–15.
- Madhumitha R, Jagadeesh C, Aditya V, Neeraj S, Nambi PS, Ram G. Isolated renal mucormycosis in an apparently healthy immune competent adult. International Journal of Medical and Health Sciences. 2017;6(2):124-6.
- Maravi-Poma E, Rodriguez-Tudela JL, de Jalon JG. Outbreak of gastric mucormycosis associated with the use of wooden tongue depressors in critically ill patients. Intensive Care Medicine 2004;30:724–8.
- Rammaert B, Lanternier F, Zahar JR, Dannaoui E, Bougnoux ME, Lecuit M, Lortholary O. Healthcare-associated mucormycosis. Clinical Infectious Diseases. 2012 Feb 1;54(suppl_1):S44-54.
- Roden MM, Zaoutis TE, Buchanan WL, Knudsen TA, Sarkisova TA, et al. Epidemiology and outcome of zygomy-cosis a review of 929 reported cases. ClinInfect Dis. 2005;41:634-653.
- Marty FM, Ostrosky-Zeichner L; Cornely OA; Mullane KM; Perfect JR; Thompson GR; Alangaden GJ; Isavuconazole treatment for mucormycosis: a single-arm open-label trial and case-control analysis. Lancet Infect Dis. 2016; 16(7):828-837
- Kontoyiannis DP; Lewis RE : How I treat mucormycosis. 2011; 118(5):1216-24.
- Sharma MC, Gill SS, Kashyap S, et al. Gastrointestinal mucormycosis—an uncommon isolated mucormycosis. Indian J Gastroenterol. 1998; 17:131-133.