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Category: Volume 06 Issue 08 August 2018
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Title: A cross-sectional Study of Pathological Findings in Cholecystectomy Specimens

Authors: Dr Priti Saini, Dr Rinku Saini, Dr Lovesh Saini, Dr Yashvi Gehlot, Dr J. P. Pankaj

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i8.63

Abstract

Introduction: Gall bladder diseases are one of the common diseases across the globe including India. These comprise the various congenital malformations, inflammatory lesions, lithiasis and malignant conditions. Inflammatory gall bladder lesions are a frequent cause of morbidity and are almost always associated with gall stones. Gall bladder carcinoma represents 20% of all gastrointestinal cancers and has a very dismal outlook. The present study was conducted to study the incidence, age and sex distribution of different gall bladder lesions including malignancy. It also studied the gross and histopathological findings of these conditions with particular reference to malignancy.

Material and Methods: A cross-sectional study was carried out in the Department of Pathology, SMS Medical College, Jaipur from June 2017 to December 2017. Approval from institutional ethics committee was taken and all the eligible specimens received to the Department of Pathology during study period were included in the study. Socio-demographic informations like, age, sex, religion and socio-economic status were taken from history sheets received with histopathological specimens.

Results: In the present study, chronic cholecystitis with lithiasis was the most common gall bladder lesion (73.33%). Benign lesions comprised 96.33% among all gall bladder lesions while malignant lesions were only 3.67%. Majority of gall bladder lesions were observed in age group 21-50 years with female predominance. All lesions were associated with gall stones except adenoma. Well differentiated adenocarcinoma was the most common carcinomatous lesion.

Conclusion: The gall bladder lesions are very common among females which are almost always associated with gall stones. So, in the presence of gall stones cholecystectomy should be indicated in women over 50 years of age to prevent gall bladder carcinoma.

Keywords: Cholecystitis, lithiasis, metaplasia, malformations, malignancy.

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Corresponding Author

Dr Rinku Saini

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