Details
Category: Volume 06 Issue 08 August 2018
Hits: 1244

Title: Role of guided Fine needle aspiration cytology in diagnosis of abdominopelvic masses

Authors: Sushma Bharti M.D, Rahul V Taksande, M.D

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i8.52

Abstract

Introduction: The introduction of modern diagnostic imaging techniques, mainly ultrasonography (USG) has enabled the detection, location and sampling of lesions at the site that are inaccessible to surgical biopsies and are considered as first step in the investigation, thereby, quickly satisfying the avidity of clinicians for a rapid diagnosis. We hereby report FNAC findings in guided FNA of abdominopelvic masses and their histopathological correlation at a tertiary care hospital.

Aims:  To assess the utility of guided Fine Needle Aspiration Cytology (FNAC) and biopsy as an initial diagnostic modality in patients with abdominopelvic masses.

Material and Methods: The study included 63 palpable and non- palpable abdominopelvic masses, which were detected clinically or radiologically. Ultrasonography/ Computed Tomography guided FNAC was done. Papanicolaou stain, H&E stain and Giemsa stains were used.

Results: Out of 63 images guided FNACs of abdominopelvic masses, non-neoplastic lesions were found in four patients and neoplastic in 56 patients. Of these 56 cases, 12 were benign and 44 malignant. In three cases, FNAC was inconclusive. Mean age of patients was 43.6 years with 30 (47.6%) males and 33 (52.38%) females. The most common organ involved was liver (15 cases) followed by ovary (13 cases). The most common malignant lesion in the liver was Hepatocellular carcinoma. Overall, the sensitivity of this study was 90.47% and specificity 100%. 

Conclusions: Guided FNAC is simple, safe and cost-effective procedure that can be utilized preoperatively, for frozen section and follow-up.

Keywords: Guided FNA, Abdominopelvic masses.

 

References

  1. Suma JK, Varna I, Aditya A. Ultrasound Guided Fnac of Abdominal–Pelvic Masses. J ClinDiagn Res 2013;7:273-7.
  2. Langlois S, Le P. Fine needle aspiration cytology. In: Orell SR, Sterrett GF, Whitaker D. Imaging methods for guidance of aspiration cytology. 4th Ed. New Delhi: Churchill Livingstone; 2005.p.31-40.
  3. Mehdi G, Maheshwari V, Afzal S, Ansari HA, Ahmad I. Image-guided fine needle aspiration of retroperitoneal masses: The role of the cytopathologist. J Cytol  2013;30:36-41.
  4. Sidhalingreddy, Andola SK. Fine Needle Aspiration Cytology of Intra- Abdominal Lesions. Journal of Clinical and Diagnostic Research 2011;5:551-8.
  5. Dosi S, Gupta G, Kawatra M, Chakrabarti PR, Agrawal P, Jain MR. Role of radiological-assisted cytology in intra-abdominal lesions: A 3 years experience in a tertiary care center. Int J App Basic Med Res 2016;6:101-5.
  6. Zawar MP, Bolde S, Shete SS. Correlative study of fine needle aspiration cytology and histology in intra abdominal lumps. SMJ 2007;4.
  7. Dhameja N , Rai V, Singh R. Fine Needle Aspiration Cytology of Liver Space Occupying Lesions - A Study of 57 Cases from a Tertiary Care Centre. IJSR 2016:5.
  8. Nasit JG, Patel V, Parikh B, Shah M, Davara K. Fine-needle aspiration cytology and biopsy in hepatic masses: A minimally invasive diagnostic approach. Clin Cancer Investig J 2013;2:132-42.
  9. Swamy MC, Arathi C, Kodandaswamy C. Value of ultrasonography-guided fine needle aspiration cytology in the investigative sequence of hepatic lesions with an emphasis on hepatocellular carcinoma. J Cytol 2011;28:178-84.
  10. Das DK, Tripathi RP, Chachra KL, Sodhani P, Parkash S, Bhambhani S. Role of guided fine needle aspiration cytology in diagnosis and classification of liver malignancies. Trop Gastroenterol 1997;18:101-6.
  11. Leiman G. Liver and Spleen. In: Orell SR, Sterret GF, Whitaker D, editors. Fine needle aspiration cytology. 4th Ed. New Delhi: Churchill Livingstone; 2005.p.293-316.
  12. Ahmad SS, Akhtar K, Akhtar SS, Alia Nasir AA, Khalid M, Mansoor T. Ultrasound Guided Fine Needle Aspiration Biopsy of Abdominal Masses. JK Science 2006;8:200-4.
  13. Sumana BS, Muniyappa B. Ultrasonography Guided Fine Needle Aspiration Cytology with Preparation of Cell Blocks in the Diagnosis of Intra- Abdominal Masses. J ClinDiagn Res 2015;9:8-12.
  14. Sanyal AJ, Yoon SK, Lencioni R. The etiology of hepatocellular carcinoma and consequences for treatment. Oncologist 2010;15 Suppl 4:14-22.
  15. Huang GT, Sheu JC, Yang PM, Lee HS, Wang TH, Chen DS. Ultrasound guided cutting biopsy for the diagnosis of hepatocellular carcinoma-a study based on 420 patients. J Hepatol 1996;25:334–8.
  16. Reddy CV, Goud YG, Poornima R, Deshmane V, Madhusudhana BA, Gayathridevi M. Role of FNAC in Hepatic lesions: Risk of track metastases. South Asian J Cancer 2015;4:35-7.
  17. Sobha Rani G, Faheem N, Sai Prasad BV, Sudhakar Reddy E. Efficiency of ultrasound guided aspiration cytology in deep seated lesions - a diagnostic evaluation. Int J Med Health Sci 2012;1:1-12.
  18. Pranab de, Subhar, Kalyan K Dhar. Fine Needle Aspiration Biopsy of Ovarian Neoplasms. Indian J PatholMicrobiol 2001;44:103-6.
  19. Mangal N, Sharma VK, Verma N, Agarwal AK, Sharma SP, Aneja S. Ultrasound guided fine needle aspiration cytology in the diagnosis of retroperitoneal masses: A study of 85 cases. J Cytol 2009;26:97-101.
  20. Chakrabarti I, Bhowmik S, Sinha MGM, Bera P. Ultrasound-guided aspiration cytology of retroperitoneal masses with histopathological corroboration: A study of 71 cases. J Cytol 2014;31:15-19.

Corresponding Author

Sushma Bharti

Address: BHEL Township, Sector 17, Type B, Qrs no. 158 C, Noida, Uttar Pradesh-201301

Phone No: 9987589704, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.