Title: Prognostic Importance of Hyponatremia in Acute ST Elevation Myocardial Infarction (STEMI)
Authors: Dr Vikas, Dr Gurdeep Kaur
DOI: https://dx.doi.org/10.18535/jmscr/v6i8.24
Abstract
Aim: To find out the prognostic importance of hyponatremia in relation with survival outcome in patients with acute STEMI.
Materials and Methods: 200 patients presenting to the emergency department of medicine of RNT medical college and associated hospital from May 2017 to November 2017, with signs and symptoms of Acute STEMI, were included in the study with their informed consent and after applying the inclusion and exclusion criteria. Plasma sodium levels were assessed on admission, and at 24hr, 48 hr and 72 hr thereafter, with hyponatremia being defined as levels less than 135 meq/l.
Results: The study comprised of 132 cases (66%) with normal sodium levels, 28 cases (14%) with hyponatremia on admission, and 40 cases (20%) who developed hyponatremia after admission within 72 hrs. Hyponatremic cases were significantly associated with higher mortality, more no. of risk factors, higher killip class, reduced ejection fraction and higher Troponin T values.
Conclusion: Hyponatremia on admission or early development of hyponatremia in patients with acute STEMI is an independent predictor of 30-day mortality, thus serving to identify patients at high risk.
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