Details
Category: Volume 05 Issue 12 December 2017
Hits: 1259

Title: Osteochondroma of Lower Dorsal Spine in Hereditary Multiple Exostosis Causing Spinal Cord Compression: Report of a Case and Review of the Literature

Authors: Ankush V Mohabey, Zilesingh Kundu, Ajay Sheoran, Umesh Yadav, Vikas Ahlawat

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i12.22

Abstract

Introduction; Osteochondroma or exostosis are the most common benign tumors of the bone that usually occur in the long bones and rarely found in the spine. When present in the spine, however, they have a predilection for the cervical region. They occur in two forms as solitary and multiple hereditary forms. We have reported here a case of spinal cord compression due to osteochondroma arising from the T-12 vertebral body and left pedicle in a 13-year-old female who presented to us with spastic paraparesis.

Keywords: Multiple Hereditary Exostosis; Osteochondroma; Spinal cord compression

References

  1. Larson NE, Dodge HW, Rushton JG, Dahlin DC. Hereditary multiple exostoses with compression of the spinal cord. Proc Staff Meet Mayo Clin. 1957;32(25):729-34.
  2. Quirini GE, Meyer JR, Herman M, Russell EJ. Osteochondroma of the thoracic spine: an unusual cause of spinal cord compression. AJNR Am J Neuroradiol. 1996;17(5):961-64.
  3. Pazzagilia UE, Perdotti L, Beluffi G, Monafo V, Savasta S. Radiographic finding in hereditary multiple exostoses and a new theory of the pathogenesis of exostoses. Pediatr Radiol. 1990;20(8):594-97.
  4. Cannon JF. Hereditary multiple exostoses. Am J Hum Genet. 1954;6(4):419-25.
  5. Larson NE, Dodge HW, Rushton JG, Dahlin DC. Hereditary multiple exostoses with compression of the spinal cord. Proc Staff Meet Mayo Clin.1957;32(25):729-34.
  6. Decker RE, Wei WC. Thoracic cord compression from multiple hereditary exostoses associated with cerebellar astrocytoma. Case report. J Neurosurg. 1969;30(3):310-12.
  7. Blaauw G. Osteocartilaginousexostosis of the spine, in Vinken PJ, Bruyn CW (eds): [6] Handbook of Clinical Neurology. Amsterdam: North Holland Publishing, Vol 19, 313– 19, 1975.
  8. Twersky J, Kassner EG, Tenner MS, Camera A. Vertebral and costal osteochondromas [7] causing spinal cord compression. Am J Roentgenol Radium TherNucl Med. 1975;124(1):124-28.
  9. Becker MH, Epstein F: Case report 77. [8] Skeletal Radiol. 1978;3:197–99.
  10. Ho SU, Lipton HL. Hereditary multiple exostoses with myelopathy. [9] Arch Neurol. 1979;36(11):714.
  11. Old WL, Triplett JN. Osteochondroma with thoracic cord compression in hereditary [10] multiple exostoses: a case report. Va Med. 1979;106(5):302-06.
  12. Buur T, Mørch MM. Hereditary multiple exostoses with spinal cord compression. [11] J Neurol Neurosurg Psychiatry. 1983;46(1):96-98.
  13. Moriwaka F, Hozen H, Nakane K, Sasaki H, Tashiro K, Abe H. Myelopathy due to [12] osteochondroma: MR and CT studies. J Comput Assist Tomogr. 1990;14(1):128-30.
  14. O’Brien MF, Bridwell KH, Lenke LG, Schoenecker PL. Intracanalicular osteoch-ondroma [13] producing spinal cord compression in hereditary multiple exostoses. J Spinal Disord. 1994;7:236–41.
  15. Govender S, Parbhoo AH. Osteoch-ondroma with compression of the spinal cord. A [14] report of two cases. J Bone Joint Surg Br. 1999;81(4):667-69.
  16. Mermer MJ, Gupta MC, Salamon PB, Benson DR. Thoracic vertebral body exostosis [15] as a cause of myelopathy in a patient with hereditary multiple exostoses. J Spinal Disord Tech. 2002;15(2):144-48.
  17. Faik A, MahfoudFilali S, Lazrak N, El Hassani S, Hajjaj-Hassouni N. Spinal cord [16] compression due to vertebral osteochondroma: report of two cases. Joint Bone Spine. 2005;72(2):177-79.
  18. Bess RS, Robbin MR, Bohlman HH, Thompson GH. Spinal exostoses: analysis of [17] twelve cases and review of the literature. Spine (Phila Pa 1976). 2005;30(7):774-80.
  19. Roach JW, Klatt JW, Faulkner ND. Involvement of the spine in patients with multiple [18] hereditary exostoses. J Bone Joint Surg Am. 2009;91(8):1942-48.
  20. Ezra N, Tetteh B, Diament M, Jonas AJ, Dickson P. Hereditary multiple exostoses with [19] spine involvement in a 4-year-old boy. Am J Med Genet A. 2010;152A(5):1264-67.
  21. Gunay C, Atalar H, Yildiz Y, Saglik Y. Spinal osteochondroma: a report on six patients [20] and a review of the literature. Arch Orthop Trauma Surg. 2010;130(12):1459-65.
  22. Lotfinia I, Vahedi P, Tubbs RS, Ghavame M, Meshkini A. Neurological manifesta-tions, [21] imaging characteristics, and surgical outcome of intraspinalosteoc-hondroma. J Neurosurg Spine. 2010;12(5):474-89.
  23. Tian Y, Yuan W, Chen H, Shen X. Spinal cord compression secondary to a thoracic [22] vertebral osteochondroma. J Neurosurg Spine. 2011;15(3):252-57.
  24. Zaijun L, Xinhai Y, Zhipeng W, Wending H, Quan H, Zhenhua Z, et al. Outcome and [23] prognosis of myelopathy and radiculopathy from osteochondroma in the mobile spine: a report on 14 patients. J Spinal Disord Tech. 2013;26(4):194-99.
  25. Bari MS, Jahangir Alam MM, Chowdhury FR, Dhar PB, Begum A. Hereditary multiple exostoses causing cord compression. J Coll Physicians Surg Pak. 2012;22(12):797-99.
  26. Al Kaissi A, Ganger R, Klaushofer K, Grill F. Spinal exostosis in a boy with multiple [25] hereditary exostoses. Case Rep Orthop. 2013;2013:758168.
  27. Calvo CE, Cruz M, Ramos E. An unusual complication in a 9-year-old patient with [26] hereditary multiple osteochondrom-atosis. PMR. 2013;5(4):348-50.
  28. Lemos MC, Kotanko P, Christie PT, et al. A novel EXT1 splice site mutation in a kindred with hereditary multiple exostosis and osteoporosis. J Clin Endocrinol Metab. 2005;90(9):5386-89.

Corresponding Author

Ankush V Mohabey

Pt.B.D.Sharma Postgraduate Institute of Medical Sciences, Rohtak

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.