Title: The Effect of Synbiotics on the Duration of Crying Time in Infants with Abdominal Colic

Authors: T.Vijayalakshmi, C.S.Balachandran, S.Chidambaranathan

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i11.139

Abstract

Objectives: Infantile colic is a condition which is seen commonly in infants that has psychosocial effects. The objective of this study was to evaluate the effectiveness of synbiotics with 4 bacterial strains - Streptococcus faecalis, Clostridium butyricum, Bacillus mesentricus and Lactobacillus sporogenes as an add on therapy to standard treatment for the management of infantile colic by measuring the reduction in mean daily crying time.

Materials and Methods: An observational, randomized, clinical study was done in Dept of Pediatrics, RMMCH, Annamalai University, Chidambaram involving fifty breastfed infants aged 30 - 180 days with abdominal colic. They were alloted into two groups- Group A and Group B by randomization. Infants in Group A were given standard treatment with Dimethicone for 5 days and infants in Group B were given standard treatment for 5 days and synbiotic for 28 days. Parents had been asked to record the crying times and the infants were followed up and the reduction in mean crying time (100 % reduction) was noted on day 7, 14 and 28.

Results: Infants assigned to synbiotic group showed rapid improvement in terms of reduction in mean daily crying time (100 % reduction – P 0.001) in comparison to standard treatment alone.

Conclusion: It was concluded from this study that it is safe, effective and beneficial to use synbiotic as an add on therapy to standard treatment to manage abdominal colic in infants.

Keywords: Infantile colic, synbiotic, Reduction in crying time.

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Corresponding Author

T.Vijayalakshmi

Post Graduate, Department of Paediatrics,

RMMCH, Chidambaram-608002, Tamilnadu, India