##plugins.themes.academic_pro.article.main##
Abstract
Background: HCV infection is the leading cause of mortaility around the world particulary in Pakistan. Hepatistis can severly damage liver which ultimately leads to the death of patient. Number of reports around the world indicate the higher rate of prvelence of HCV infection, these rate are higehr in Asian and underdeveopled countries. We therefore have setu up crosssectional study to assess the HCV infection in the residents of three union councils of Jamshoro District.
Methodology: The study was conducted for the period of six months from january 2013 to june 2013. The data was obtained by structured interview based questionnaire comprised of questions about transmission of risk factors and awareness of HCV. Serum was obtained by centrifuging the blood and HCV was detected using Elisa Kit.
Results: Total 662 subjects were randomly selected for the study, out of which 351 (53%) males and 311 (47%) were females. The over all prevalnce rate of HCV positive cases was recorded as 128 (19.33%), Of these 128, 71(55.5%) were males and 57(45.5%) were females. HCV infection was common in all age groups and overall the level of awareness was very low, and ven in lower in case of tranmission of HCV infection from one person to other person.
Conclusion: HCV is increasing day by day in the residents of targeted Union councils, and the residents are less aware about the prevention measures, practical steps are needed to aware them from causes of HCV.
Keywords: Prevalence, Awareness, Hepatitis C, Jamshoro.##plugins.themes.academic_pro.article.details##
References
2. Abdul Mujeeb, S., D. Nanan, et al. (2006). "Hepatitis B and C infection in first-time blood donors in Karachi--a possible subgroup for sentinel surveillance." East Mediterr Health J 12(6): 735-741.
3. Ahmad, N., M. Asgher, et al. (2007). "An evidence of high prevalence of Hepatitis C virus in Faisalabad, Pakistan." Saudi Med J 28(3): 390-395.
4. Alter, M. J. (2007). "Epidemiology of hepatitis C virus infection." World J Gastroenterol 13(17): 2436-2441.
5. Aslam, M. and J. Aslam (2001). "Seroprevalence of the antibody to hepatitis C in select groups in the Punjab region of Pakistan." J Clin Gastroenterol 33(5): 407-411.
6. Attaullah, S., S. Khan, et al. (2011). "Hepatitis C virus genotypes in Pakistan: a systemic review." Virol J 8: 433.
7. Aziz, S., R. Khanani, et al. (2010). "Frequency of hepatitis B and C in rural and periurban Sindh." J Pak Med Assoc 60(10): 853-857.
8. Bari, A., S. Akhtar, et al. (2001). "Risk factors for hepatitis C virus infection in male adults in Rawalpindi-Islamabad, Pakistan." Trop Med Int Health 6(9): 732-738.
9. Butt, T. and M. S. Amin (2008). "Seroprevalence of hepatitis B and C infections among young adult males in Pakistan." East Mediterr Health J 14(4): 791-797.
10. De Cock, K. M., P. M. Simone, et al. (2013). "The new global health." Emerg Infect Dis 19(8): 1192-1197.
11. El-Serag, H. B. (2007). "Epidemiology of hepatocellular carcinoma in USA." Hepatol Res 37 Suppl 2: S88-94.
12. Gower, E., C. C. Estes, et al. (2014). "Global epidemiology and genotype distribution of the hepatitis C virus infection." J Hepatol.
13. Idrees, M. and S. Riazuddin (2008). "Frequency distribution of hepatitis C virus genotypes in different geographical regions of Pakistan and their possible routes of transmission." BMC Infect Dis 8: 69.
14. Jamil, M. S., H. Ali, et al. (2010). "Prevalence, knowledge and awareness of hepatitis C among residents of three Union Councils in Mansehra." J Ayub Med Coll Abbottabad 22(3): 192-196.
15. Khattak, M. N., S. Akhtar, et al. (2008). "Factors influencing Hepatitis C virus sero-prevalence among blood donors in north west Pakistan." J Public Health Policy 29(2): 207-225.
16. Khokhar, N., M. L. Gill, et al. (2004). "General seroprevalence of hepatitis C and hepatitis B virus infections in population." J Coll Physicians Surg Pak 14(9): 534-536.
17. Lee, M. H., H. I. Yang, et al. (2014). "Epidemiology and natural history of hepatitis C virus infection." World J Gastroenterol 20(28): 9270-9280.
18. Maasoumy, B. and H. Wedemeyer (2012). "Natural history of acute and chronic hepatitis C." Best Pract Res Clin Gastroenterol 26(4): 401-412.
19. Mohd Hanafiah, K., J. Groeger, et al. (2013). "Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence." Hepatology 57(4): 1333-1342.
20. Moore, Z. S., M. K. Schaefer, et al. (2011). "Transmission of hepatitis C virus during myocardial perfusion imaging in an outpatient clinic." Am J Cardiol 108(1): 126-132.
21. Mujeeb, S. A. (2001). "Unsafe injections: a potential source of HCV spread in Pakistan." J Pak Med Assoc 51(1): 1-3.
22. Qureshi, H., A. Arif, et al. (2007). "HCV exposure in spouses of the index cases." J Pak Med Assoc 57(4): 175-177.
23. Raja, N. S. and K. A. Janjua (2008). "Epidemiology of hepatitis C virus infection in Pakistan." J Microbiol Immunol Infect 41(1): 4-8.
24. Rathore, J. A., M. A. Shah, et al. (2012). "Hepatitis C virus transmission risk factors." J Ayub Med Coll Abbottabad 24(3-4): 106-108.
25. Shaikh, F. H., H. Ali Abro, et al. (2009). "Hepatitis C: frequency and risk factors associated with sero-positivity among adults in Larkana City." J Ayub Med Coll Abbottabad 21(2): 107-109.
26. Shaikh, M. A., W. M. Shaikh, et al. (2003). "Frequency and transmission mode of hepatitis C virus in northern Sindh." J Coll Physicians Surg Pak 13(12): 691-693.
27. Shepard, C. W., L. Finelli, et al. (2005). "Global epidemiology of hepatitis C virus infection." Lancet Infect Dis 5(9): 558-567.
28. Sievert, W., I. Altraif, et al. (2011). "A systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt." Liver Int 31 Suppl 2: 61-80.
29. Strickland, G. T. (2010). "Risk factors for HCV infection in Pakistan." J Viral Hepat 17(5): 305-306.